近年来，纳米技术在医学领域的应用受到了密切关注，这主要是由于将设计好的材料从实验室有效地转化到临床的过程存在诸多挑战。COVID-19大流行期间使用的mRNA疫苗巩固了过去几十年来对纳米技术支持的医疗保健纳米粒子药物递送材料研究的新兴趣。同时得益于细胞生物学和基因工程的进展，这为下一代生物制剂药物递送发展铺平了道路。在该特刊中，我们突出强调创新研究是如何应对这些类型材料有限的靶向性、低载量和高生产成本等挑战的。
特刊全部文章：
https://pubs.acs.org/page/cmatex/vi/drug-delivery
1
Breaking with Light: Stimuli-Responsive Mesoporous Organosilica Particles
Pierre Picchetti, Brian N. DiMarco, Leana Travaglini*, Yang Zhang, M. Carmen Ortega-Liebana, and Luisa De Cola*
Chem. Mater. 2020, 32, 1, 392-399
2
Azobenzene-Based Cross-Linked Small-Molecule Vesicles for Precise Oxidative Damage Treatments Featuring Controlled and Prompt Molecular Release
Yongchao Yao, Yunlong Yu, Xiaohui Wan, Daoping Yan, Ying Chen, Jianbin Luo, G. Julius Vancso, and Shiyong Zhang*
Chem. Mater. 2021, 33, 18, 7357-7366
3
General Approach for Machine Learning-Aided Design of DNA-Stabilized Silver Clusters
Stacy M. Copp*, Steven M. Swasey, Alexander Gorovits, Petko Bogdanov, and Elisabeth G. Gwinn*
Chem. Mater. 2020, 32, 1, 430-437
4
High Loading Capacity Nanoencapsulation and Release of Hydrophobic Drug Nanocrystals from Microgel Particles
Trystan Domenech and Patrick S. Doyle*
Chem. Mater. 2020, 32, 1, 498-509
5
Programmable Electrostatic Interactions Expand the Landscape of Dynamic Functional Hydrogels
Sheng-Chen Huang, Xiao-Xia Xia, Ru-Xia Fan, and Zhi-Gang Qian*
Chem. Mater. 2020, 32, 5, 1937-1945
6
Polymer-Based Microneedles for Decentralized Diagnostics and Monitoring: Concepts, Potentials, and Challenges
Samuel Babity, Elise Laszlo, and Davide Brambilla*
Chem. Mater. 2021, 33, 18, 7148-7159
7
Nucleic Acids Based Polyelectrolyte Complexes: Their Complexation Mechanism, Morphology, and Stability
Young Hun Kim, Kwanghee Lee, and Sheng Li*
Chem. Mater. 2021, 33, 20, 7923-7943
8
Nano-assembly of a Chemically Tailored Cas9 Ribonucleoprotein for In Vivo Gene Editing and Cancer Immunotherapy
Juhee Lee, Yoo Kyung Kang, Eonju Oh, Juhee Jeong, San Hae Im, Duk Ki Kim, Haeshin Lee, Sang-Gyu Kim, Keehoon Jung*, and Hyun Jung Chung*
Chem. Mater. 2022, 34, 2, 547-561
9
Template-Assisted Antibody Assembly: A Versatile Approach for Engineering Functional Antibody Nanoparticles
Yingjie Hu, Jianhua Li, Yi Ju, Zachary H. Houston, Nicholas L. Fletcher, Robert De Rose, Soraia Fernandes, Christoph E. Hagemeyer, Karen Alt, Kristofer J. Thurecht, Christina Cortez-Jugo, and Frank Caruso*
Chem. Mater. 2022, 34, 8, 3694-3704
阅读Chem. Mater.特刊 “The Future of Healthcare Materials” 全部文章：
https://pubs.acs.org/page/cmatex/vi/drug-delivery
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